Adult Reference Ranges for Serum Cystatin C, Creatinine and Predicted Creatinine Clearance

Relationship between Serum Creatinine, Cystatin-C and Creatinine Clearance in Chronic Kidney Disease

Recommendations for laboratory diagnosis and monitoring of chronic kidney disease (CKD) state the use of both serum creatinine and cystatin-C in various clinical situations. The relationship of these markers to estimated glomerular filtration rate (eGFR) is found to be different in different populations. In India the routine reporting of eGFR is yet to commence. Meanwhile, the utility of these ...

Reference ranges for plasma cystatin C and creatinine measurements in premature infants, neonates, and older children.

AIM To establish a reference range in the paediatric population for the new glomerular filtration rate (GFR) marker, cystatin C, and to compare it with that of creatinine. METHODS Cystatin C and creatinine were measured by particle enhanced nephelometric immunoassay (PENIA) and fixed interval Jaff¿e methods, respectively, in 291 children aged 1 day to 17 years, including 30 premature infants ...

Serum cystatin C is a better marker of topotecan clearance than serum creatinine.

PURPOSE To evaluate plasma cystatin level as a covariate to predict topotecan pharmacokinetics. Cystatin C, a member of the cystatin superfamily of cysteine proteinase inhibitors, has been recently proposed as an alternative endogenous marker of glomerular filtration. Renal function is known as a key factor of topotecan clearance. EXPERIMENTAL DESIGN Data were obtained from 59 patients who un...

Correlation of serum concentrations of cystatin C and creatinine to inulin clearance in liver cirrhosis.

Spreadsheet use to calculate creatinine clearance from serum creatinine.

Spreadsheets may be created to include the Cockcroft-Gault Formula (CGF) for creatinine-based estimation of glomerular filtration rate. Creatinine clearance (CrCl) provides a more accurate method for perioperative risk assessment of renal function than serum creatinine. CrCl may be used to develop guidelines for renal protective management strategies during cardiopulmonary bypass. CGF uses seru...